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Category:Technical writingA simple test for calculation of the combined daily dosage of antihypertensive drugs.
A simple test to calculate the combined daily dosage of any two given drugs for the treatment of hypertension is suggested. The two drugs are combined in the ratio of their therapeutic indexes, expressed as the ratio of their antihypertensive activity divided by their toxicity. This ratio is employed to choose the therapeutic dosage of the more active of the two drugs. The calculations for any two drugs of interest are performed as follows. First, the effective hypotensive activity (NE/D) of the two drugs is determined by using a two-week hypotensive study to determine the hypotensive activity of each of the drugs. This activity is expressed as a percentage of the maximum level of hypotension (E/Dmax) obtained with a standard dose of the most active drug. In addition, an estimation of the lethal activity of the two drugs is made by dividing the ED50 (where D is the dose of the standard drug in milligrams per kilogram body weight) by the maximum non-toxic dose (MD) of the most active drug. Next, the toxicity (Tox) of the two drugs is determined by using the lethal activity ratios (LAR = Tox1/E1, Tox2/E2) of the two drugs. Finally, the combined activity ratio (CAR) is
AutoCAD 20.0 Crack+ License Key Full
Open the menu “Plugins”.
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1. Field of the Invention
The present invention relates to a needle guard for a syringe, and more particularly to a needle guard of a syringe in which a needle is moved along with a plunger rod from a rearward end to a front end of a barrel, and being retracted into the barrel by the forward movement of the plunger rod.
2. Description of the Prior Art
Generally, a syringe generally comprises a barrel having a needle mounted on a front end thereof for penetrating a skin of a person, a plunger rod inserted in a rear end of the barrel, and a needle guard mounted in the front end of the barrel for guiding the needle during the movement of the needle.
In the conventional syringe, when the needle is mounted on the barrel and moved to a front end of the barrel, the needle moves by an inertia force in a rearward direction. Therefore, the forward movement of the plunger rod is needed for retracting the needle into the barrel.
In this conventional syringe, the needle is moved from the rear end of the barrel toward the front end thereof. Thereafter, the needle is moved to the front end of the barrel by the inertia force. The forward movement of the plunger rod pushes the needle into the barrel, and the needle is then retracted into the barrel.
However, since the needle is pushed toward the front end of the barrel by the plunger rod, the needle is moved not along with the movement of the plunger rod but against the movement of the plunger rod. That is, the needle is always moved by the inertia force. Accordingly, the conventional syringe is very dangerous to the user. In addition, the conventional syringe is complicated in structure and large in size.
U.S. Pat. No. 4,626,250 discloses a similar needle guard for a syringe. In this U.S. Pat. No. 4,626,250, a needle is moved along with a plunger rod by an inertia force
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